Musing from Mars has published an update of his Ajax Framework Browser compatibility review. It’s not a framework review but rather a rating of how compatible these frameworks are with all of the major browser versions. His grading scale is simple: the more versions of browsers you support, the better. See below.
A - IE 6, Firefox 1.0, Safari 1.2, Opera, Other DOM-compliant
B - IE 6, Firefox 1.x, Safari 2.x, Other DOM-compliant
C - IE 6, Firefox 1.x, Other DOM-compliant
D - IE 6, Firefox 1.5
E - IE 6
I’m not sure I agree with his grading scale (what grade does a framework that only supports Opera get?), but no matter. Some information is better than none. Some of the highlights? Echo2: A; ZK: D+ (Safari problems and insufficient testing); Tibco GI: E (tied to IE with very lame Firefox support).

[Ajax / DHTML] Ajax/DHTML Framework/Browser Compatibility Ratings
The weblog Musings from Mars has put together
Not sure I agree with the grading either but the article does include videos of how different browsers represent different things – which is very useful indeed!
ZK supports Safari and Camino as well now.
There are tools available nowadays for browser compatibility testing which can reveal the areas that are incompatible across browsers. infact when i have to fix BCT problems, i found http://www.essentiabct.com very useful tool.